Individualized rTMS neuronavigated according to regional brain metabolism ((18)FGD PET) has better treatment effects on auditory hallucinations than standard positioning of rTMS: a double-blind, sham-controlled study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43906471" target="_blank" >RIV/00216208:11120/13:43906471 - isvavai.cz</a>
Alternative codes found
RIV/00023752:_____/13:43914161
Result on the web
<a href="http://dx.doi.org/10.1007/s00406-012-0368-x" target="_blank" >http://dx.doi.org/10.1007/s00406-012-0368-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00406-012-0368-x" target="_blank" >10.1007/s00406-012-0368-x</a>
Alternative languages
Result language
angličtina
Original language name
Individualized rTMS neuronavigated according to regional brain metabolism ((18)FGD PET) has better treatment effects on auditory hallucinations than standard positioning of rTMS: a double-blind, sham-controlled study
Original language description
Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) of the left temporo-parietal cortex (LTPC) has been proposed as a useful therapeutic method for auditory hallucinations (AHs). Stereotactic neuronavigation enables the magnetic coil tobe targeted according to the individual parameters obtained from neuroimaging. Individualized rTMS neuronavigated according to 18-fluorodeoxyglucose positron emission tomography ( 18FDG PET) allows us to focus the coil explicitly on a given area with detected maxima of specific abnormalities, thus presuming a higher therapeutic effect of the method. The objective of this study is to test clinical efficacy of neuronavigated LF-rTMS administered according to the local maxima of 18FDG PET uptake of LTPC and to compare it with treatment effects of standard and sham rTMS. In a double-blind, sham-controlled design, patients with AHs underwent a 10-day series of LF-rTMS using (1) 18FDG PET-guided "neuronavigation," (2) "standard" anatomically
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0517" target="_blank" >1M0517: Center of Neuropsychiatric Studies 2005-2009 (Neurobiology in Clinical Application)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Archives of Psychiatry and Clinical Neuroscience
ISSN
0940-1334
e-ISSN
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Volume of the periodical
263
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
475-484
UT code for WoS article
000323513800004
EID of the result in the Scopus database
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