Essentials of circulating tumor cells for clinical research and practice
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907832" target="_blank" >RIV/00216208:11120/13:43907832 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.critrevonc.2013.05.002" target="_blank" >http://dx.doi.org/10.1016/j.critrevonc.2013.05.002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.critrevonc.2013.05.002" target="_blank" >10.1016/j.critrevonc.2013.05.002</a>
Alternative languages
Result language
angličtina
Original language name
Essentials of circulating tumor cells for clinical research and practice
Original language description
The major cause of death due to cancer is its metastatic deposit in numerous tissues and organs. The metastatic process requires the migration of malignant cells from primary sites to distant environments. Even for tumors initially spreading through lymphatic vessels, hematogenous transport is the most common metastatic pathway. The detachment of cancer cells from a primary tumor into the blood stream is called epithelial mesenchymal transition (EMT). As these cells circulate further in the bloodstreamthey are known as circulating tumor cells (CTCs). The CTC population is highly resilient, enabling the cells to colonize a foreign microenvironment. Alternatively, cancer stem cells (CSCs) may arise from differentiated cancer cells through EMT and an embryonic transdifferentiation process. The presence of CTCs/CSCs in blood seems to be a determining factor of metastasis. This paper reviews various methods of clinical cancer detection as well as the biology and molecular characterization
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Critical Reviews in Oncology Hematology
ISSN
1040-8428
e-ISSN
—
Volume of the periodical
88
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
338-356
UT code for WoS article
000326776200009
EID of the result in the Scopus database
—