Management of Hypotension in Preterm Infants (The HIP Trial): A Randomised Controlled Trial of Hypotension Management in Extremely Low Gestational Age Newborns

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908573" target="_blank" >RIV/00216208:11120/14:43908573 - isvavai.cz</a>

Alternative codes found

RIV/00023698:_____/14:#0000171

Result on the web

<a href="http://dx.doi.org/10.1159/000357553" target="_blank" >http://dx.doi.org/10.1159/000357553</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000357553" target="_blank" >10.1159/000357553</a>

Result language

angličtina

Original language name

Management of Hypotension in Preterm Infants (The HIP Trial): A Randomised Controlled Trial of Hypotension Management in Extremely Low Gestational Age Newborns

Original language description

Background: Extremely preterm babies (delivered at <28 completed weeks of gestation) are frequently diagnosed with hypotension and treated with inotropic and pressor drugs in the immediate postnatal period. Dopamine is the most commonly used first-line drug. Babies who are treated for hypotension more frequently sustain brain injury, have long-term disability or die compared to those who are not. Despite the widespread use of drugs to treat hypotension in such infants, evidence for efficacy is lacking,and the effect of these agents on long-term outcomes is unknown. Hypothesis: In extremely preterm babies, restricting the use of dopamine when mean blood pressure (BP) values fall below a nominal threshold and using clinical criteria to determine escalation of support ('restricted' approach) will result in improved neonatal and longer-term developmental outcomes. Research Plan: In an international multi-centre randomised trial, 830 infants born at <28 weeks of gestation, and within 72 h

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FG - Paediatrics

OECD FORD branch

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Project

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Continuities

R - Projekt Ramcoveho programu EK

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neonatology

ISSN

1661-7800

e-ISSN

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Volume of the periodical

105

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

275-281

UT code for WoS article

000336879100006

EID of the result in the Scopus database

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