Epithelial cell morphology and adhesion on diamond films deposited and chemically modified by plasma processes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908867" target="_blank" >RIV/00216208:11120/14:43908867 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1116/1.4890471" target="_blank" >http://dx.doi.org/10.1116/1.4890471</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1116/1.4890471" target="_blank" >10.1116/1.4890471</a>
Alternative languages
Result language
angličtina
Original language name
Epithelial cell morphology and adhesion on diamond films deposited and chemically modified by plasma processes
Original language description
The authors show that nanocrystalline diamond (NCD) thin films prepared by microwave plasma enhanced chemical vapor deposition apparatus with a linear antenna delivery system are well compatible with epithelial cells (5637 human bladder carcinoma) and significantly improve the cell adhesion compared to reference glass substrates. This is attributed to better adhesion of adsorbed layers to diamond as observed by atomic force microscopy (AFM) beneath the cells. Moreover, the cell morphology can be adjusted by appropriate surface treatment of diamond by using hydrogen and oxygen plasma. Cell bodies, cytoplasmic rims, and filopodia were characterized by Peakforce AFM. Oxidized NCD films perform better than other substrates under all conditions (96% of cells adhered well). A thin adsorbed layer formed from culture medium and supplemented with fetal bovine serum (FBS) covered the diamond surface and played an important role in the cell adhesion. Nevertheless, 50-100 nm large aggregates forme
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
JI - Composite materials
OECD FORD branch
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Result continuities
Project
<a href="/en/project/KAN200100801" target="_blank" >KAN200100801: Bioactive Biocompatible Surfaces and Novel Nanostructured Composites for Applications to Medicine and Drug Delivery</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biointerphases
ISSN
1934-8630
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
"Article ID 031012; 1-8"
UT code for WoS article
000340893400013
EID of the result in the Scopus database
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