The effect of acclimatization and ambient temperature on heat withdrawal threshold in rats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43908433" target="_blank" >RIV/00216208:11120/15:43908433 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/ejp.515" target="_blank" >http://dx.doi.org/10.1002/ejp.515</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ejp.515" target="_blank" >10.1002/ejp.515</a>

Result language
angličtina
Original language name
The effect of acclimatization and ambient temperature on heat withdrawal threshold in rats
Original language description
Nociception in rats is frequently measured in terms of latency of withdrawal reaction to radiant heat (thermal nociceptive threshold). The aim of this study was to determine how much housing acclimatization and ambient temperature affect the results of thermal pain threshold testing. All experiments used adult male Wistar rats. Thermal pain thresholds were tested using the radiant heat withdrawal reaction at three different body sites: forepaws, hind paws and tail. Skin temperature was measured using anInfrared thermometer and ambient temperature was set at 18, 20, 24 or 26 °C. The results demonstrate that (1) thermal pain threshold was inversely related to both ambient and skin temperature; (2) housing acclimatization and repeated testing had no effect on nociceptive thresholds at any of the three body sites; (3) a resting, cranio-caudal distribution, of nociceptive sensitivity was observed; (4) hind paws and tail were more sensitive to changes of skin and ambient temperature than fo
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Project
<a href="/en/project/NT14484" target="_blank" >NT14484: Combination of opioid analgesics and psychostimulants in the treatment of chronic pain</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)