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Association of Fibroblast Growth Factor-23 Levels and Angiotensin-Converting Enzyme Inhibition in Chronic Systolic Heart Failure

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43910498" target="_blank" >RIV/00216208:11120/15:43910498 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023001:_____/15:00059572 RIV/00216208:11110/15:10313829 RIV/00064190:_____/15:#0001101

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.jchf.2015.05.012" target="_blank" >http://dx.doi.org/10.1016/j.jchf.2015.05.012</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jchf.2015.05.012" target="_blank" >10.1016/j.jchf.2015.05.012</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Association of Fibroblast Growth Factor-23 Levels and Angiotensin-Converting Enzyme Inhibition in Chronic Systolic Heart Failure

  • Original language description

    OBJECTIVES The aim of this study was to evaluate the association of fibroblast growth factor (FGF)-23 with clinical and laboratory findings, the prognostic value of FGF-23, and the relationship between angiotensin-converting enzyme inhibitor (ACEi) therapy, FGF-23 levels, and outcomes in patients with chronic systolic heart failure (HF). BACKGROUND FGF-23 is a bone-derived hormone regulating mineral metabolism. Higher FGF-23 levels are associated with an increased risk of cardiovascular mortality or HFdevelopment. Mechanisms leading to increased FGF-23 and its prognostic value have not been thoroughly studied in HF. METHODS FGF-23 was measured in 369 patients (mean age 59 +/- 11 years, 84% male) with systolic HF. Patients were followed for adverse events (e.g., death, urgent heart transplantation, ventricular assist device implantation). RESULTS Tricuspid regurgitation severity, chronic kidney disease (CKD), alkaline phosphatase concentrations, inferior vena cava dilation, and absence

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JACC: Heart Failure

  • ISSN

    2213-1779

  • e-ISSN

  • Volume of the periodical

    3

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    829-839

  • UT code for WoS article

    000365656200012

  • EID of the result in the Scopus database

    2-s2.0-84943418755