Procalcitonin Dynamics After Long-Term Ventricular Assist Device Implantation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F17%3A43912904" target="_blank" >RIV/00216208:11120/17:43912904 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/17:00075972
Result on the web
<a href="http://dx.doi.org/10.1016/j.hlc.2016.09.014" target="_blank" >http://dx.doi.org/10.1016/j.hlc.2016.09.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.hlc.2016.09.014" target="_blank" >10.1016/j.hlc.2016.09.014</a>
Alternative languages
Result language
angličtina
Original language name
Procalcitonin Dynamics After Long-Term Ventricular Assist Device Implantation
Original language description
BACKGROUND: Infectious complications (IC) are one of the main causes of worsening prognosis after long-term ventricular assist device (LVAD) implantation. Procalcitonin (PCT) is widely used for diagnosis of a bacterial infection. The objective of this study was to assess PCT dynamics after LVAD surgery and their relationship to the infectious complications. METHODS: A total of 25 consecutive patients indicated for LVAD implantation as a bridge to heart transplant were included. Procalcitonin levels were prospectively assessed before surgery and during the postoperative period (day 1, 2, 14 and 30). Values were compared according to the presence of IC. RESULTS: Procalcitonin levels were low before surgery, raised significantly within 1st and 2nd day after operation and decreased in the 14th and 30th days back to the baseline. There was no significant difference in PCT values between patients with or without IC as well as with or without right ventricle assist device (RVAD). Acute renal failure (ARF) increased PCT significantly only 14 days after LVAD implantation. In patients with ARF and/or RVAD we observed significantly higher PCT values in the 2nd, 14(th) and 30(th) day after operation. In subjects with IC and/or ARF and/or RVAD we also observed significantly elevated PCT concentrations 2 and 14 days after surgery. CONCLUSIONS: Our data show that the ability of PCT to detect IC in patients after LVAD implantation is limited and its concentrations more likely correlate with postoperative complications in general.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Heart, Lung and Circulation
ISSN
1443-9506
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
6
Country of publishing house
AU - AUSTRALIA
Number of pages
5
Pages from-to
599-603
UT code for WoS article
000402467300011
EID of the result in the Scopus database
2-s2.0-85009723999