Menthol-based hydrophobic deep eutectic solvents: Towards greener and efficient extraction of phytocannabinoids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F18%3A43916760" target="_blank" >RIV/00216208:11120/18:43916760 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/18:10376799 RIV/00216208:11110/18:10376799 RIV/00023752:_____/18:43919391 RIV/00064165:_____/18:10376799

Result on the web

<a href="https://doi.org/10.1016/j.jclepro.2018.05.080" target="_blank" >https://doi.org/10.1016/j.jclepro.2018.05.080</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jclepro.2018.05.080" target="_blank" >10.1016/j.jclepro.2018.05.080</a>

Result language

angličtina

Original language name

Menthol-based hydrophobic deep eutectic solvents: Towards greener and efficient extraction of phytocannabinoids

Original language description

As the demand for medical cannabis preparations increases, so does the use of the common organic solvents that are used in the extraction and quantification of phytocannabinoids. Since common organic solvents are typically hazardous to the environment and to human health, it is vital to identify safer, greener, and more efficient alternatives. The aim of the present research was to develop a series of hydrophobic deep eutectic solvents (DESs) based on terpenes and natural organic acids and to establish whether these might be potential substitutes for the extraction of phytocannabinoids (tetrahydrocannabinol, cannabidiol, and their carboxylated homologues) from raw cannabis plant material. Data were obtained using capillary electrophoresis with diode array detection (DAD). Initial screening showed that the DES composed of a menthol: acetic acid (1:1 M ratio) mixture showed the greatest extraction efficiency (of all the DESs that were tested), with yields ranging from 118.6% to 132.6% (compared to a methanol: chloroform mixture). In conclusion, menthol: acetic acid DES extraction is efficient, as well as non-toxic and biodegradable. As such it has applications within the pharmaceutical industry and represents a greener alternative organic solvent for the extraction of phytocannabinoids.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10406 - Analytical chemistry

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Cleaner Production

ISSN

0959-6526

e-ISSN

—

Volume of the periodical

193

Issue of the periodical within the volume

August

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

391-396

UT code for WoS article

000437997200032

EID of the result in the Scopus database

2-s2.0-85048201921