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Intralaboratory comparison of analytical methods for quantification of major phytocannabinoids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389030%3A_____%2F19%3A00505428" target="_blank" >RIV/61389030:_____/19:00505428 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/19:73596980 RIV/00027006:_____/19:00005103

  • Result on the web

    <a href="http://doi.org/10.1007/s00216-019-01760-y" target="_blank" >http://doi.org/10.1007/s00216-019-01760-y</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00216-019-01760-y" target="_blank" >10.1007/s00216-019-01760-y</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intralaboratory comparison of analytical methods for quantification of major phytocannabinoids

  • Original language description

    This study compares alternative approaches for analyzing phytocannabinoids in different plant materials. Three chromatographic analytical methods (ultra-high-performance liquid chromatography with tandem mass spectrometric detection and gas chromatography with mass spectrometric and flame ionization detection) were evaluated regarding selectivity, sensitivity, analytical accuracy, and precision. The performance of the methods was compared and all three methods were demonstrated to be appropriate tools for analyzing phytocannabinoids in cannabis. Gas chromatography coupled with mass spectrometric detection showed slightly better accuracy in determining phytocannabinoid acids, which are often difficult to quantify owing to their limited stability. Aspects of sample preparation, such as material homogenization and extraction, were also considered. A single ultrasonic-assisted ethanolic extraction of dried and powdered plant samples of cannabis was shown to be exhaustive for extracting the samples prior to analysis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    <a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical and Bioanalytical Chemistry

  • ISSN

    1618-2642

  • e-ISSN

  • Volume of the periodical

    411

  • Issue of the periodical within the volume

    14

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    11

  • Pages from-to

    3069-3079

  • UT code for WoS article

    000468293800008

  • EID of the result in the Scopus database

    2-s2.0-85063188200