Within-subject biological variation of pairs of heavy/light immunoglobulin IgM chains (HLC IgM kappa and lambda) is low and requires monitoring: A comparison with HLC IgA, HLC IgG, and free light immunoglobulin chains (FLC) in healthy subjects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F18%3A43917005" target="_blank" >RIV/00216208:11120/18:43917005 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/18:00077378
Result on the web
<a href="https://doi.org/10.1016/j.cca.2018.08.023" target="_blank" >https://doi.org/10.1016/j.cca.2018.08.023</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cca.2018.08.023" target="_blank" >10.1016/j.cca.2018.08.023</a>
Alternative languages
Result language
angličtina
Original language name
Within-subject biological variation of pairs of heavy/light immunoglobulin IgM chains (HLC IgM kappa and lambda) is low and requires monitoring: A comparison with HLC IgA, HLC IgG, and free light immunoglobulin chains (FLC) in healthy subjects
Original language description
The serum free light immunoglobulin chains (FLC) belong to the well characterized and widely used standard methods in patients with multiple myeloma (MM), monoclonal gammopathy of undetermined significance (MGUS), and other plasma cell dyscrasias, together with serum protein electrophoresis, immunofixation, and bone marrow examination. The serum pairs of heavy/light immunoglobulin chains (HLC) play an increasing role in the diagnosis and monitoring of monoclonal gammopathies. Data describing biological variation of serum pairs of heavy/light immunoglobulin chains (HLC) IgA, HLC IgG, and free light immunoglobulin chains (FLC) are scarce, and data on variation of HLC IgM are missing. The aim was to acquire data on the variation of HLC IgM κ and λ and to verify the variation of HLC IgA, IgG, and FLC.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
<a href="/en/project/NV15-27579A" target="_blank" >NV15-27579A: Monoclonal gammopathies in solid organ transplant recipients. Relationship between posttransplant immunosuppression and lymphoproliferative diseases.</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinica Chimica Acta
ISSN
0009-8981
e-ISSN
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Volume of the periodical
486
Issue of the periodical within the volume
November
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
2
Pages from-to
311-312
UT code for WoS article
000447481400053
EID of the result in the Scopus database
2-s2.0-85052241506