Bioptically Proven "Anticoagulation-Related Nephropathy" Induced by Dual Antiplatelet Therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F18%3A43917170" target="_blank" >RIV/00216208:11120/18:43917170 - isvavai.cz</a>

Alternative codes found

RIV/00023001:_____/18:00077630

Result on the web

<a href="https://doi.org/10.1159/000493093" target="_blank" >https://doi.org/10.1159/000493093</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000493093" target="_blank" >10.1159/000493093</a>

Result language

angličtina

Original language name

Bioptically Proven "Anticoagulation-Related Nephropathy" Induced by Dual Antiplatelet Therapy

Original language description

Anticoagulation-related nephropathy (ARN) is a significant and underdiagnosed complication in patients who receive anticoagulation therapy. It is characterized by acute kidney injury in the setting of excessive anticoagulation defined as an international normalized ratio &gt; 3.0 in patients treated with warfarin. A definitive diagnosis is made by renal biopsy showing acute tubular necrosis with obstruction of the tubuli by red blood cell casts. However, the evidence shows that ARN can occur during treatment with novel oral anticoagulants as well. Although it has been suggested that antiplatelet therapy, such as aspirin, might contribute to coagulopathy (and therefore the hypothetical risk of ARN), there are no reports of ARN induced by antiplatelet therapy according to our knowledge. It is also reported that glomerular lesions (i.e., kidney disease) represent a risk factor for ARN. We present a case of an 82-year-old man who developed biopsy-proven ARN after the administration of dual antiplatelet therapy with no previous anticoagulation treatment and normal coagulation tests.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30217 - Urology and nephrology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Case Reports in Nephrology and Dialysis

ISSN

2296-9705

e-ISSN

—

Volume of the periodical

8

Issue of the periodical within the volume

3

Country of publishing house

CH - SWITZERLAND

Number of pages

7

Pages from-to

216-222

UT code for WoS article

000456460900004

EID of the result in the Scopus database

2-s2.0-85054542859