All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Secretory carcinoma of salivary type in a lymph node presenting as a neck cyst diagnosed by cytology: A case report

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43920298" target="_blank" >RIV/00216208:11120/21:43920298 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11110/21:10412887 RIV/00064165:_____/21:10412887 RIV/00064173:_____/21:N0000143

  • Result on the web

    <a href="https://doi.org/10.1002/dc.24550" target="_blank" >https://doi.org/10.1002/dc.24550</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/dc.24550" target="_blank" >10.1002/dc.24550</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Secretory carcinoma of salivary type in a lymph node presenting as a neck cyst diagnosed by cytology: A case report

  • Original language description

    Secretory carcinoma (SC) is a relatively recently described salivary gland adenocarcinoma characterized by ETV6-NTRK3 gene fusion and, in most cases, indolent clinical behavior. Morphologically, the tumor shows a glandular architecture and the presence of monophasic tumor cells with vacuolated cytoplasm, low-grade nuclear atypia, and mucin production, with possibly a tubular, papillary, or cystic arrangement. In this article, we describe a case of a 52-year old man with SC involving a neck lymph node clinically manifesting as a slowly growing cystic neck mass without recent proof of the primary tumor, but with a history of a parotid gland &quot;cystadenopapilloma,&quot; which had been removed 35 years prior. A fine-needle aspiration biopsy revealed a diagnosis of SC. Subsequent histopathological examination after lymph node dissection confirmed the diagnosis. The tumor showed typical features of SC, including immunohistochemical positivity for NTRK and NTRK3 gene rearrangement, detected using in situ hybridization. We discuss that the tumor may be a late metastasis occurring 35 years after resection of undiagnosed salivary SC or a primary SC arising from heterotopic salivary tissue within a lymph node. Differential diagnostic considerations and review of relevant literature are included.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30109 - Pathology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Diagnostic Cytopathology

  • ISSN

    8755-1039

  • e-ISSN

  • Volume of the periodical

    49

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    "e1"-"e6"

  • UT code for WoS article

    000550399200001

  • EID of the result in the Scopus database

    2-s2.0-85088160270