The Slavcleft: A three-center study of the outcome of treatment of cleft lip and palate. Nasolabial appearance
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921204" target="_blank" >RIV/00216208:11120/21:43921204 - isvavai.cz</a>
Alternative codes found
RIV/00064173:_____/21:N0000263 RIV/61989592:15110/21:73611404
Result on the web
<a href="https://doi.org/10.7717/peerj.10631" target="_blank" >https://doi.org/10.7717/peerj.10631</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.7717/peerj.10631" target="_blank" >10.7717/peerj.10631</a>
Alternative languages
Result language
angličtina
Original language name
The Slavcleft: A three-center study of the outcome of treatment of cleft lip and palate. Nasolabial appearance
Original language description
Background: There is a multitude of protocols of treatment of cleft lip and palate (CLP) worldwide differing in number of operations, surgical techniques, and timings of surgeries. Despite, facial appearance in subjects with CLP is rarely ideal and residual stigmata are easy to notice in many patients irrespective of the protocol. The prospective controlled investigations are optimal for comparing effectiveness of treatment protocols. Because prospective studies are very challenging to perform in CLP field, it is reasonable to retrospectively assess different surgical protocols to identify the promising ones and then to test them in a prospective way. Methods: Our objective was to assess the nasolabial appearance in a preadolescent Slavic population with unilateral cleft lip and palate (UCLP) by using the 0 200 numeric scale with reference photographs. Patients treated in Warsaw, Poland (n = 32), Prague, Czech Republic (n = 26) and Bratislava, Slovakia (n = 17) were included in this retrospective study. Each cleft center used a unique surgical protocol. Two panels of professional raters (n = 7) and laypeople (n = 10) scored blindly the nasolabial esthetics on cropped frontal and profile images with cropped reference photograph present on the same slide. Intra-and inter-rater agreement was assessed with Cronbach s alpha, intraclass correlation coefficients, t-Tests, and Bland Altman plots. Inter-group differences were evaluated with one-way ANOVA and regression analysis. Results: The agreement within and between raters was acceptable. We found that patients treated in Warsaw, Prague, and Bratislava showed comparable nasolabial appearance on frontal and profile photographs when judged by both professional raters (p 0.05) and laypeople (p 0.05). Regression analysis did not identify influence of gender, group (i.e., Warsaw, Prague, and Bratislava), age at lip repair, surgeon, and age at photographic assessment on esthetic outcome (p 0.05). Conclusion: This study showed that none of the surgical protocols showed superiority to produce good nasolabial appearance.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30208 - Dentistry, oral surgery and medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PeerJ
ISSN
2167-8359
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
February
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
"e10631"
UT code for WoS article
000616406800006
EID of the result in the Scopus database
2-s2.0-85101022405