Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921940" target="_blank" >RIV/00216208:11120/21:43921940 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/21:N0000084

Result on the web

<a href="https://doi.org/10.1111/jce.15233" target="_blank" >https://doi.org/10.1111/jce.15233</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jce.15233" target="_blank" >10.1111/jce.15233</a>

Result language

angličtina

Original language name

Novel approach to diagnosis of His bundle capture using individualized left ventricular lateral wall activation time as reference

Original language description

BACKGROUND: During non-selective His bundle (HB) pacing, it is clinically important to confirm His bundle capture vs. right ventricular septal (RVS) capture. The present study aimed to validate the hypothesis that during HB capture, left ventricular lateral wall activation time, approximated by the V(6) R-wave peak time (V(6) RWPT), will not be longer than the corresponding activation time during native conduction. METHODS: Consecutive patients with permanent HB pacing were recruited; cases with abnormal His-ventricle interval or left bundle branch block were excluded. Two corresponding intervals were compared: stimulus-V(6) RWPT and native HBpotential-V(6) RWPT. The difference between these two intervals (delta V(6) RWPT), which was diagnostic of lack of HB capture, was identified using receiver operating characteristic (ROC) curve analysis. RESULTS: A total of 723 ECGs (219 with native rhythm, 172 with selective HB, 215 with non-selective HB, and 117 with RVS capture) were obtained from 219 patients. The native HB-V(6) RWPT, non-selective-, and selective-HB paced V(6) RWPT were nearly equal, while RVS V(6) RWPT was 32.0 (+-9.5) ms longer. The ROC curve analysis indicated delta V(6) RWPT &gt; 12 ms as diagnostic of lack of HB capture (specificity of 99.1% and sensitivity of 100%). A blinded observer correctly diagnosed 96.7% (321/332) of ECGs using this criterion. CONCLUSIONS: We validated a novel criterion for HB capture that is based on the physiological left ventricular activation time as an individualized reference. HB capture can be diagnosed when paced V(6) RWPT does not exceed the value obtained during native conduction by more than 12 ms, while longer paced V(6) RWPT indicates RVS capture.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Cardiovascular Electrophysiology

ISSN

1045-3873

e-ISSN

—

Volume of the periodical

32

Issue of the periodical within the volume

11

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

3010-3018

UT code for WoS article

000692640400001

EID of the result in the Scopus database

2-s2.0-85114103985