Diabetes in stiff-person syndrome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F23%3A43925955" target="_blank" >RIV/00216208:11120/23:43925955 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.tem.2023.07.005" target="_blank" >https://doi.org/10.1016/j.tem.2023.07.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.tem.2023.07.005" target="_blank" >10.1016/j.tem.2023.07.005</a>
Alternative languages
Result language
angličtina
Original language name
Diabetes in stiff-person syndrome
Original language description
Anti-glutamic acid decarboxylase (GAD) autoantibodies are a hallmark of stiff-person syndrome (SPS) and insulin-dependent diabetes mellitus (IDDM). However, patients with concurrent IDDM and SPS often manifest insulin resistance, and SPS-associated IDDM probably has heterogeneous causes. Some patients manifest IDDM associated only with high titers of anti-GAD65 caused by SPS. By contrast, other patients develop IDDM only after being treated with high-dose corticosteroids or they progress to insulin dependency following their treatment with high-dose corticosteroids. The profile of autoantibodies differs markedly between type 1 diabetes mellitus (T1DM), late-onset diabetes mellitus, and SPS-associated IDDM. Therefore, as with new-onset diabetes after transplantation (NODAT), SPS-associated IDDM should be classified as a specific diabetes entity, the pathophysiology of which requires increased attention.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
<a href="/en/project/NU23-06-00045" target="_blank" >NU23-06-00045: Development of an in vitro model for the study of renal dysfunction due to pharmacotherapy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Trends in Endocrinology & Metabolism
ISSN
1043-2760
e-ISSN
1879-3061
Volume of the periodical
34
Issue of the periodical within the volume
10
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
640-651
UT code for WoS article
001079253900001
EID of the result in the Scopus database
2-s2.0-85168336494