Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F09%3A5529" target="_blank" >RIV/00216208:11130/09:5529 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/09:5529
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response
Original language description
The primary function of the immune system is to protect the host against pathogens.Success of vaccination diseases has led to efforts to develop strategies to activate a specific immune response against cancer. However,this task has proved to be very challenging.In the last few years there has been rapid progress in the identification of the molecular mechanisms by which the immune system detects pathogens and initiates immune responses. By contrast, recognition of neoplastic cells lags behind, and induction of specific anti-tumour immunity is even less understood.In this chapter we discuss evidence for the role of the immune system in the control of tumour growth. We also rewiev recent advances in the understanding of mechanisms that can alert the immune system ti the presence of neoplastic lesions, and we discuss recent data on the immunogenicity of tumour cells and their interaction with presenting cells.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA310%2F08%2F0838" target="_blank" >GA310/08/0838: Generation of dendritic cell-based vaccines for ovarian cancer immunotherapy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Phagocytosis of Dying Cells: From Molecular Mechanism to Human Disease
ISBN
978-1-4020-9292-3
Number of pages of the result
24
Pages from-to
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Number of pages of the book
447
Publisher name
Springer
Place of publication
Belgie
UT code for WoS chapter
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