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A simple drug anchoring microfiber scaffold for chondrocyte seeding and proliferation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F12%3A8032" target="_blank" >RIV/00216208:11130/12:8032 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/12:00377778 RIV/61389013:_____/12:00377778 RIV/46747885:24410/12:#0001137 RIV/62157124:16170/12:43871413 RIV/68407700:21460/12:00202567

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s10856-011-4518-x" target="_blank" >http://dx.doi.org/10.1007/s10856-011-4518-x</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A simple drug anchoring microfiber scaffold for chondrocyte seeding and proliferation

  • Original language description

    The structural properties of microfiber meshes made from poly(2-hydroxyethyl methacrylate) (PHEMA) were found to significantly depend on the chemical composition and subsequent cross-linking and nebulization processes. PHEMA microfibres showed promise asscaffolds for chondrocyte seeding and proliferation. Moreover, the peak liposome adhesion to PHEMA microfiber scaffolds observed in our study resulted in the development of a simple drug anchoring system. Attached foetal bovine serum-loaded liposomes significantly improved both chondrocyte adhesion and proliferation. In conclusion, fibrous scaffolds from PHEMA are promising materials for tissue engineering and, in combination with liposomes, can serve as a simple drug delivery tool.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Materials Science-Materials in Medicine

  • ISSN

    0957-4530

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    555-563

  • UT code for WoS article

    000301640800035

  • EID of the result in the Scopus database