Nanofibers prepared by needleless electrospinning technology as scaffolds for wound healing

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F12%3A8288" target="_blank" >RIV/00216208:11130/12:8288 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/12:00379338 RIV/61389013:_____/12:00379338 RIV/68378050:_____/12:00379338 RIV/00216208:11120/12:43901656 and 2 more

Result on the web

<a href="http://dx.doi.org/10.1007/s10856-012-4577-7" target="_blank" >http://dx.doi.org/10.1007/s10856-012-4577-7</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Nanofibers prepared by needleless electrospinning technology as scaffolds for wound healing

Original language description

Electrospun gelatin and poly-epsilon-caprolactone (PCL) nanofibers were prepared using needleless technology and their biocompatibility and therapeutic efficacy have been characterized in vitro in cell cultures and in an experimental model of a skin wound. The effect of nanofibers on wound healing was examined using a full thickness wound model in rats and compared with a standard control treatment with gauze. Significantly faster wound closure was found with gelatin after 5 and 10 days of treatment, but no enhancement with PCL nanofibers was observed. Histological analysis revealed enhanced epithelialisation, increased depth of granulation tissue and increased density of myofibroblasts in the wound area with gelatin nanofibers. The results show that gelatin nanofibers produced by needleless technology accelerate wound healing and may be suitable as a scaffold for cell transfer and skin regeneration.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Materials Science-Materials in Medicine

ISSN

0957-4530

e-ISSN

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Volume of the periodical

23

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

931-941

UT code for WoS article

000302345400008

EID of the result in the Scopus database

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