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Thyroid carcinoma surgery in children and adolescents - 15 years experience surgery of pediatric thyroid carcinoma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F14%3A10288142" target="_blank" >RIV/00216208:11130/14:10288142 - isvavai.cz</a>

  • Alternative codes found

    RIV/61383082:_____/14:#0000261 RIV/00216208:11110/14:10288142 RIV/00216208:11120/14:43908601 RIV/00023761:_____/14:#0000444 RIV/00064203:_____/14:10288142

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.ijporl.2014.03.005" target="_blank" >http://dx.doi.org/10.1016/j.ijporl.2014.03.005</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ijporl.2014.03.005" target="_blank" >10.1016/j.ijporl.2014.03.005</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Thyroid carcinoma surgery in children and adolescents - 15 years experience surgery of pediatric thyroid carcinoma

  • Original language description

    Objectives: The purpose of this study is to evaluate the characteristics of thyroid gland surgery focusing on malignancies at the pediatric age with the main concern on treatment results and complications in extensive primary treatment. Methods: The records of all patients 18 years and younger with surgically treated thyroid diseases in the Prague Hospital, Motol, between 1991 and 2006 were retrospectively reviewed. Results: Thyroid surgery was performed on 148 pediatric patients (including 56 carcinomas). The youngest patient involved in the study was seven years old, the oldest patient 18 years old (mean 13.7 years). Most frequent histological cancer type was PTC (42 cases, 75%). Follicular cancer was diagnosed in five cases (8.9%) and medullar cancer in nine cases (16.1%). A prophylactic thyroidectomy was performed in three cases (5.4%) without clinical signs of thyroid tumor with diagnosed RET gene mutation. Conclusions: We consider total thyroidectomy with subsequent radioiodine ablation and TSH suppression as the basic approach in the treatment protocol of pediatric WDTC. The observed 100% recurrence-free and overall survival together with a low incidence of postoperative complications strongly supports the idea of a total thyroidectomy with selective neck dissection in the treatment of metastases of WDTC and MTC.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30206 - Otorhinolaryngology

Result continuities

  • Project

    <a href="/en/project/NT11455" target="_blank" >NT11455: Long term follow up of patients with low risk thyroid carcinoma, elaboration of algorithm of optimal therapy</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Pediatric Otorhinolaryngology

  • ISSN

    0165-5876

  • e-ISSN

  • Volume of the periodical

    78

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

    990-994

  • UT code for WoS article

    000338608100005

  • EID of the result in the Scopus database

    2-s2.0-84902085844