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BCOR and BCORL1 mutations in pediatric acute myeloid leukemia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10295003" target="_blank" >RIV/00216208:11130/15:10295003 - isvavai.cz</a>

  • Alternative codes found

    RIV/00064203:_____/15:10295003

  • Result on the web

    <a href="http://dx.doi.org/10.3324/haematol.2014.117796" target="_blank" >http://dx.doi.org/10.3324/haematol.2014.117796</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.3324/haematol.2014.117796" target="_blank" >10.3324/haematol.2014.117796</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    BCOR and BCORL1 mutations in pediatric acute myeloid leukemia

  • Original language description

    Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the presence of different collaborating cytogenetic and molecular aberrations that are associated with treatment response. Approximately 20% of pediatric AML patients are classifiedas cytogenetically normal AML (CN-AML). In the past decade, new prognostic relevant aberrations have been identified in CN-AML, such as NPM1, WT1, FLT3-ITD and CEBPA double mutations (CEBPAdm), which may improve future risk-group stratification. In addition to these mutations, we recently described recurrent cryptic NUP98/NSD1 and NUP98/KDM5A translocations in pediatric CN-AML.9,10 Still, some CN-AML samples have not been fully characterized.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Haematologica

  • ISSN

    0390-6078

  • e-ISSN

  • Volume of the periodical

    100

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    IT - ITALY

  • Number of pages

    2

  • Pages from-to

  • UT code for WoS article

    000354788000010

  • EID of the result in the Scopus database

    2-s2.0-84929170408