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Structural alterations of the language connectome in children with specific language impairment

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10315261" target="_blank" >RIV/00216208:11130/15:10315261 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985807:_____/15:00451407 RIV/00064203:_____/15:10315261

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bandl.2015.10.003" target="_blank" >http://dx.doi.org/10.1016/j.bandl.2015.10.003</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bandl.2015.10.003" target="_blank" >10.1016/j.bandl.2015.10.003</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Structural alterations of the language connectome in children with specific language impairment

  • Original language description

    We evaluated brain white matter pathways associated with language processing in 37 children with specific language impairment aged 6-12 years and 34 controls, matched for age, sex and handedness. Arcuate fascicle (AF), inferior fronto-occipital fascicle(IFOF), inferior longitudinal fascicle (ILF) and uncinate fascicle (UF) were identified using magnetic resonance diffusion tensor imaging (DTI). Diffusivity parameters and volume of the tracts were compared between the SLI and control group. Children with SLI showed decreased fractional anisotropy in all investigated tracts, increased mean diffusivity and radial diffusivity component in arcuate fascicle bilaterally, left IFOF and left ILF. Further, bilaterally increased volume of the ILF in children with SLI was found. We confirmed previous findings indicating deficient connectivity of the arcuate fascicle and as a novel finding, demonstrate abnormal development of the ventral language stream in patients with SLI.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NT11443" target="_blank" >NT11443: Computer analysis of speech expression, EEG records and MR tractography in children with developmental dysphasia</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Brain and Language

  • ISSN

    0093-934X

  • e-ISSN

  • Volume of the periodical

    151

  • Issue of the periodical within the volume

    neuvedeno

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    35-41

  • UT code for WoS article

    000367122300004

  • EID of the result in the Scopus database

    2-s2.0-84947711345