Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316073" target="_blank" >RIV/00216208:11130/15:10316073 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/15:10316073

Result on the web

<a href="http://dx.doi.org/10.3324/haematol.2014.116707" target="_blank" >http://dx.doi.org/10.3324/haematol.2014.116707</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3324/haematol.2014.116707" target="_blank" >10.3324/haematol.2014.116707</a>

Result language

angličtina

Original language name

Minimal residual disease analysis by eight-color flow cytometry in relapsed childhood acute lymphoblastic leukemia

Original language description

Multiparametric flow cytometry is an alternative approach to the polymerase chain reaction method for evaluating minimal residual disease in treatment protocols for primary acute lymphoblastic leukemia. Given considerable differences between primary andrelapsed acute lymphoblastic leukemia treatment regimens, flow cytometric assessment of minimal residual disease in relapsed leukemia requires an independent comprehensive investigation. In the present study we addressed evaluation of minimal residual disease by flow cytometry in the clinical trial for childhood relapsed acute lymphoblastic leukemia using eight-color flow cytometry. The major challenge of the study was to reliably identify low amounts of residual leukemic cells against the complex background of regeneration, characteristic of follow-up samples during relapse treatment. In a prospective study of 263 follow-up bone marrow samples from 122 patients with B-cell precursor acute lymphoblastic leukemia, we tested various B-cel

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

<a href="/en/project/NT13462" target="_blank" >NT13462: Optimization of immunotherapy and flow cytometric minimal residual disease assessment in resistant acute lymphoblastic leukaemia</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Haematologica

ISSN

0390-6078

e-ISSN

—

Volume of the periodical

100

Issue of the periodical within the volume

7

Country of publishing house

IT - ITALY

Number of pages

10

Pages from-to

935-944

UT code for WoS article

000361196400024

EID of the result in the Scopus database

2-s2.0-84936074533