Primary Whipple disease of the brain: case report with long-term clinical and MRI follow-up
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316166" target="_blank" >RIV/00216208:11130/15:10316166 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2147/NDT.S92066" target="_blank" >http://dx.doi.org/10.2147/NDT.S92066</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/NDT.S92066" target="_blank" >10.2147/NDT.S92066</a>
Alternative languages
Result language
angličtina
Original language name
Primary Whipple disease of the brain: case report with long-term clinical and MRI follow-up
Original language description
Whipple disease (WD) is a rare systemic disorder caused by the bacteria Tropheryma whipplei. In its classic form, it manifests with gastrointestinal problems including diarrhea, abdominal pain, and weight loss. However, various other systems can be affected, including the central nervous system (CNS). Even more rarely, the CNS is primarily affected without gastrointestinal symptoms and with a negative small bowel biopsy. The incidence of primary CNS WD is unknown. We report the case of a young female with the primary CNS form of WD. In this report, we highlight the main clinical features and diagnostic procedures that lead to the diagnosis and comment on the treatment and clinical response. We stress the importance of neuroimaging and brain biopsy. A unique feature of this case is that the patient has been followed up for 12 years. At the time of diagnosis, no neurological manifestations were detected, although a tumor-like lesion in the right temporal lobe and hypothalamic infiltratio
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuropsychiatric Disease and Treatment
ISSN
1178-2021
e-ISSN
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Volume of the periodical
11
Issue of the periodical within the volume
září
Country of publishing house
NZ - NEW ZEALAND
Number of pages
9
Pages from-to
2461-2469
UT code for WoS article
000362324600001
EID of the result in the Scopus database
2-s2.0-84942848581