Biomarkers of Brain Damage: S100B and NSE Concentrations in Cerebrospinal Fluid-A Normative Study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316205" target="_blank" >RIV/00216208:11130/15:10316205 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2015/379071" target="_blank" >http://dx.doi.org/10.1155/2015/379071</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2015/379071" target="_blank" >10.1155/2015/379071</a>
Alternative languages
Result language
angličtina
Original language name
Biomarkers of Brain Damage: S100B and NSE Concentrations in Cerebrospinal Fluid-A Normative Study
Original language description
NSE and S100B belong among the so-called structural proteins of the central nervous system (CNS). Lately, this group of structural proteins has been profusely used as specific biomarkers of CNS tissue damage. So far, the majority of the research papers have focused predominantly on the concentrations of these proteins in blood in relation to CNS damage of various origins. Considering the close anatomic and functional relationship between the brain or spinal cord and cerebrospinal fluid (CSF), in case ofa CNS injury, a rapid and pronounced increase of the concentrations of structural proteins specifically in CSF takes place. This study inquires into the physiological concentrations of NSE and S100B proteins in CSF, carried out on a sufficiently large group of 601 patients. The detected values can be used for determination of a normal reference range in CSF in a clinical laboratory diagnostics.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioMed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
neuveden
Issue of the periodical within the volume
září
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
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UT code for WoS article
000361202100001
EID of the result in the Scopus database
2-s2.0-84941702902