Acid-base disorders associated with serum electrolyte patterns in patients on hemodiafiltration

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316394" target="_blank" >RIV/00216208:11130/15:10316394 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/15:10316394 RIV/00064203:_____/15:10316394
Result on the web
<a href="http://dx.doi.org/10.1016/j.nephro.2015.04.008" target="_blank" >http://dx.doi.org/10.1016/j.nephro.2015.04.008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.nephro.2015.04.008" target="_blank" >10.1016/j.nephro.2015.04.008</a>

Result language
angličtina
Original language name
Acid-base disorders associated with serum electrolyte patterns in patients on hemodiafiltration
Original language description
Background. - Metabolic acidosis (MAC) is a common aspect of dialysis-dependent patients. It is definitely caused by acid retention; however, the influence of other plasma ions is unclear. Understanding the mechanism of MAC and its correction is important when choosing the dialysis solution. Therefore, we assessed the relationship between intradialytic change of acid-base status and serum electrolytes. Methods. - We studied 68 patients on post-dilution hemodiafiltration, using dialysate bicarbonate concentration 32 mmol/L. The acid-base disorders were evaluated by the traditional Siggaard-Anderson and modern Stewart approaches. Results. - The mean pre-dialysis pH was 7.38, standard base excess (SBE) -1.5, undetermined anions (UA-) 7.5, sodium-chloridedifference (Diff(NaCl)) 36.2 mmol/L. MAC was present in 34% of patients, of which 83% had an increased UA- as a major cause of MAC. The mean nPCR was 0.99 g/kg/day and correlated negatively with SBE. After dialysis, metabolic alkalosis pr
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Project
<a href="/en/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedical Centre of the Faculty of Medicine in Pilsen</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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