Colorectal cancer in patients under the age of 40 years: experience from a tertiary care centre in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10373179" target="_blank" >RIV/00216208:11130/17:10373179 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00099601 RIV/00064203:_____/17:10373179

Result on the web

<a href="http://dx.doi.org/10.1080/00015458.2017.1321270" target="_blank" >http://dx.doi.org/10.1080/00015458.2017.1321270</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00015458.2017.1321270" target="_blank" >10.1080/00015458.2017.1321270</a>

Result language

angličtina

Original language name

Colorectal cancer in patients under the age of 40 years: experience from a tertiary care centre in the Czech Republic

Original language description

Introduction: Colorectal cancer (CRC) in young patients is not an uncommon disease. Reports on its behaviour in young patients are conflicting. The aim of this study was to investigate patient and tumour characteristics, treatment and prognosis of this disease. Methods: Our study group comprised all patients under the age of 40 years treated with CRC at the Department of Surgery at Motol University Hospital in Prague between the years 2005 and 2015. Results: Thirty-eight patients under 40 years of age diagnosed with CRC were included in the study. Five patients had Lynch syndrome and six had first-degree relatives with CRC. There were 22 rectal tumours. All but four patients underwent resection of the primary tumour, all patients received chemotherapy and 13 patients received biological therapy. Disease recurrence occurred in 25.8%. Five-year survival was 47.9%. Advanced disease and adverse histological subtypes were identified as poor prognostic factors. Conclusions: Colorectal cancer in young patients has a high incidence of predisposing conditions, aggressive histological features and advanced disease. Young patients are of a good state of health and thus should receive aggressive therapy. Clinicians should pay more attention to symptoms of CRC in young patients to be able to initiate early treatment.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta Chirurgica Belgica

ISSN

0001-5458

e-ISSN

—

Volume of the periodical

117

Issue of the periodical within the volume

6

Country of publishing house

BE - BELGIUM

Number of pages

7

Pages from-to

356-362

UT code for WoS article

000419273900002

EID of the result in the Scopus database

2-s2.0-85018256270