A t(4;19) pediatric undifferentiated sarcoma with a novel variant of the CIC-DUX4 fusion transcript
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10373665" target="_blank" >RIV/00216208:11130/17:10373665 - isvavai.cz</a>
Alternative codes found
RIV/00064203:_____/17:10373665
Result on the web
<a href="https://doi.org/10.1016/j.prp.2016.12.005" target="_blank" >https://doi.org/10.1016/j.prp.2016.12.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.prp.2016.12.005" target="_blank" >10.1016/j.prp.2016.12.005</a>
Alternative languages
Result language
angličtina
Original language name
A t(4;19) pediatric undifferentiated sarcoma with a novel variant of the CIC-DUX4 fusion transcript
Original language description
We report cytogenetic and molecular genetic analysis of a pediatric tumor positive for the CIC-DUX4 fusion. The tumor belongs to a rare, diagnostically challenging subgroup of undifferentiated small round cell sarcomas. A balanced t(4;19)(q35;q13.1-2) was identified by G-banding, as a sole cytogenetic finding. The translocation was also identified by the M-FISH technique. After RT-PCR, the tumor sample was positive for the CIC-DUX4 fusion. The PCR product contains a novel, so far unreported variant of the CICDUX4 fusion transcript, with a fusion of the exon 20 from the CIC gene and the exon 1 from the DUX4 gene.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology: Research and Practice
ISSN
0344-0338
e-ISSN
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Volume of the periodical
213
Issue of the periodical within the volume
3
Country of publishing house
DE - GERMANY
Number of pages
5
Pages from-to
281-285
UT code for WoS article
000397371700019
EID of the result in the Scopus database
2-s2.0-85008323128