Should Bariatric Surgery be Performed in Children and Adolescents with Hypothalamic Obesity?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F17%3A10373802" target="_blank" >RIV/00216208:11130/17:10373802 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/17:10373802

Result on the web

<a href="https://doi.org/10.17458/per.vol14.2017.SBP.FD.Bariatric" target="_blank" >https://doi.org/10.17458/per.vol14.2017.SBP.FD.Bariatric</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17458/per.vol14.2017.SBP.FD.Bariatric" target="_blank" >10.17458/per.vol14.2017.SBP.FD.Bariatric</a>

Result language

angličtina

Original language name

Should Bariatric Surgery be Performed in Children and Adolescents with Hypothalamic Obesity?

Original language description

Hypothalamic dysfunction leading to severe obesity is a serious long-term consequence of paediatric craniopharyngioma. It compromises quality of life, leads to long-term metabolic hazards, and may shorten life expectancy. Therefore, a proactive approach is required. Conventional treatment of hypothalamic obesity is difficult and hardly successful. Experience with bariatric surgery is limited, especially in younger patients. Two retrospective studies recently reported on classic bariatric surgery in a small series of individuals after craniopharyngioma. Of these, one included nine paediatric patients who underwent laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB) or biliopancreatic diversion (BPD). The immediate effects were promising: The mean weight loss was 20.9 kilograms at 6 months and 15.1 kilograms at 12 months. A duodenal-jejunal bypass sleeve (DBJS; EndoBarrier) is a mini-invasive, endoscopically placed and fully reversible bariatric procedure. We reported a boy diagnosed with craniopharyngioma at 10 years old who underwent surgery and radiotherapy. His body weight increased to 139 kilograms and body mass index (BMI) to 46.1 kg/m(2) (+4.0 SD) within the subsequent 4.5 years. Fifteen months after DJBS placement, he lost 32.8 kilograms, and his BMI dropped to 32.7 kg/m(2) (+2.9 SD). Thus, DJBS proved to be a promising procedure in the treatment of hypothalamic obesity. We suggest performing it in children and adolescents with hypothalamic obesity to prevent or attenuate its devastating long-term sequelae.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

30202 - Endocrinology and metabolism (including diabetes, hormones)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů