Benzathine penicillin G once-every-3-week prophylaxis for recurrent erysipelas a retrospective study of 132 patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10375389" target="_blank" >RIV/00216208:11130/18:10375389 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/18:W0000140
Result on the web
<a href="https://doi.org/10.1080/09546634.2017.1329507" target="_blank" >https://doi.org/10.1080/09546634.2017.1329507</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/09546634.2017.1329507" target="_blank" >10.1080/09546634.2017.1329507</a>
Alternative languages
Result language
angličtina
Original language name
Benzathine penicillin G once-every-3-week prophylaxis for recurrent erysipelas a retrospective study of 132 patients
Original language description
Objective: To evaluate effectivity, safety and patients' adherence to benzathine penicillin G (BPG) 1,200,000 units (1.2MU) once-every-3-week intramuscularly prophylaxis for recurrent erysipelas.Methods: Patients with documented two or more erysipelas episodes in last two years who received at least one of 10 planned doses of BPG 1.2MU intramuscularly between January 2009 and December 2015 were analyzed in this retrospective study. Number of recurrences during the 30-week prophylaxis and in the 30-week follow-up period, frequency of adverse events, patients' adherence to the treatment and factors associated with the recurrence were analyzed.Results: From 132 patients, 109 (82.6%) finished the 30-week prophylactic regimen successfully. The incidence of erysipelas was 8 per 100 patient-years during the prophylactic period and 28 per 100 patient-years in the follow-up period (incidence rate ratio=0.20; 95% CI: 0.05-0.34; p<.01). In univariate analysis recurrence was significantly associated only with presence of any local risk factor concurrently with obesity (OR 3.40; 95% CI: 1.10-10.50; p<.05).Conclusion: Benzathine penicillin G 1.2MU once every 3weeks is an effective and well-tolerated prophylaxis of recurrent erysipelas with good patient adherence to the treatment. Further studies to determine the appropriate duration of prophylaxis are necessary.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30216 - Dermatology and venereal diseases
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Dermatological Treatment
ISSN
0954-6634
e-ISSN
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Volume of the periodical
29
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
39-43
UT code for WoS article
000423855400009
EID of the result in the Scopus database
2-s2.0-85019681675