Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10393480" target="_blank" >RIV/00216208:11130/18:10393480 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-319-93485-3_3" target="_blank" >https://doi.org/10.1007/978-3-319-93485-3_3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-93485-3_3" target="_blank" >10.1007/978-3-319-93485-3_3</a>

Result language
angličtina
Original language name
Neural Stem Cells Derived from Human-Induced Pluripotent Stem Cells and Their Use in Models of CNS Injury
Original language description
Induced pluripotent stem (iPS) cells are derived from differentiated cells by different reprogramming techniques, by introducing specific transcription factors responsible for pluripotency. Induced pluripotent stem cells can serve as an excellent source for differentiated neural stem/progenitor cells (NSCs/NPs). Several methods and protocols are utilized to create a robust number of NSCs/NPs without jeopardizing the safety issues required for in vivo applications. A variety of disease-specific iPS cells have been used to study nervous system diseases. In this chapter, we will focus on some of the derivation and differentiation approaches and the application of iPS-NPs in the treatment of spinal cord injury and stroke. (C) 2018, Springer International Publishing AG, part of Springer Nature.
Czech name
—
Czech description
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Project
<a href="/en/project/GBP304%2F12%2FG069" target="_blank" >GBP304/12/G069: Project of excellence in the field of neuroscience</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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