Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00073605" target="_blank" >RIV/00216224:14110/14:00073605 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/14:00061024
Result on the web
<a href="http://dx.doi.org/10.1155/2014/512831" target="_blank" >http://dx.doi.org/10.1155/2014/512831</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2014/512831" target="_blank" >10.1155/2014/512831</a>
Alternative languages
Result language
angličtina
Original language name
Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools
Original language description
Human pluripotent stem cells (hPSCs), namely, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with their ability of indefinite self-renewal and capability to differentiate into cell types derivatives of all three germlayers, represent a powerful research tool in developmental biology, for drug screening, disease modelling, and potentially cell replacement therapy. Efficient differentiation protocols that would result in the cell type of our interest are needed for maximal exploitation of these cells. In the present work, we aim at focusing on the protocols for differentiation of hPSCs into functional cardiomyocytes in vitro as well as achievements in the heart disease modelling and drug testing on the patient-specific iPSC-derived cardiomyocytes (iPSC-CMs).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioMed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
2014
Issue of the periodical within the volume
"512831"
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
1-14
UT code for WoS article
000334221200001
EID of the result in the Scopus database
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