Five years of improving diabetes control in Czech children after the establishmet of the population-based childhood diabetes register ČENDA

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F20%3A10398805" target="_blank" >RIV/00216208:11130/20:10398805 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/20:10398805 RIV/00216208:11320/20:10398805 RIV/00179906:_____/20:10398805 RIV/00669806:_____/20:10398805 RIV/00064203:_____/20:10398805

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=4coO7reu9O" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=4coO7reu9O</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/pedi.12929" target="_blank" >10.1111/pedi.12929</a>

Result language

angličtina

Original language name

Five years of improving diabetes control in Czech children after the establishmet of the population-based childhood diabetes register ČENDA

Original language description

Objectives The Czech National Childhood Diabetes Register (CENDA) is a web-based nationwide database that collects treatment and outcome data in children and adolescents with diabetes. Here, we present data from the first 5 years of CENDA (2013-2017). Methods Data include characteristics of disease onset and annual summaries of key clinical care parameters from every patient treated by participating pediatric diabetes outpatient clinics. Results The database contains data of 4361 children (aged 0-19 years) from 52 centers (85% of all Czech pediatric patients). Of these, 94% had type 1 diabetes (T1D), 4.5% had genetically proven monogenic or secondary, and 1.5% had type 2 diabetes. In children with T1D, median glycated hemoglobin (HbA1c) decreased throughout the observed period from 66.3 to 61.0 mmol/mol (P &lt; .0001, 95% confidence interval [CI] for change -5.6 to -4 mmol/mol). Consequently, the proportion of children reaching the target therapeutic goal of 58.5 mmol/mol increased from 28% in 2013 to 40% in 2017. The proportion of children treated with insulin pumps (CSII) remained stable over the observed period (25%). In a subanalysis of 1602 patients (long-standing T1D diagnosed before 2011), the main predictors associated with lower HbA1c were treatment with CSII, male sex and care provided at a large diabetes center (&gt;100 patients). Conclusions A significant continuous decrease in HbA1c was observed in Czech children over the past 5 years. As this improvement was not accompanied by appreciable changes in the mode of therapy, we assume that the establishment of our nationwide register has itself constituted a stimulus towards improvement in the care process.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30209 - Paediatrics

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pediatric Diabetes

ISSN

1399-543X

e-ISSN

—

Volume of the periodical

21

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

77-87

UT code for WoS article

000490350900001

EID of the result in the Scopus database

2-s2.0-85074412693