Anti-Müllerian hormone as an ovarian reserve marker in women with the most frequent muscular dystrophies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F20%3A10412671" target="_blank" >RIV/00216208:11130/20:10412671 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/20:00116134 RIV/65269705:_____/20:00072837 RIV/00064203:_____/20:10412671
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=OJcerc5xqJ" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=OJcerc5xqJ</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/MD.0000000000020523" target="_blank" >10.1097/MD.0000000000020523</a>
Alternative languages
Result language
angličtina
Original language name
Anti-Müllerian hormone as an ovarian reserve marker in women with the most frequent muscular dystrophies
Original language description
Some muscular dystrophies may have a negative impact on fertility. A decreased ovarian reserve is 1 of the factors assumed to be involved in fertility impairment. AMH (anti-Müllerian hormone) is currently considered the best measure of ovarian reserve.A total of 21 females with myotonic dystrophy type 1 (MD1), 25 females with myotonic dystrophy type 2 (MD2), 12 females with facioscapulohumeral muscular dystrophy (FSHD), 12 female carriers of Duchenne muscular dystrophy mutations (cDMD) and 86 age-matched healthy controls of reproductive age (range 18 - 44 years) were included in this case control study. An enzymatically amplified 2-site immunoassay was used to measure serum AMH level.The MD1 group shows a significant decrease of AMH values (median 0.7 ng/mL; range 0 - 4.9 ng/mL) compared with age-matched healthy controls (P < .01). AMH levels were similar between patients and controls in terms of females with MD2 (P = .98), FSHD (P = .55) and cDMD (P = .60).This study suggests decreased ovarian reserve in women with MD1, but not in MD2, FSHD and cDMD.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medicine
ISSN
0025-7974
e-ISSN
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Volume of the periodical
99
Issue of the periodical within the volume
23
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
e20523
UT code for WoS article
000549892300041
EID of the result in the Scopus database
2-s2.0-85086051166