Cognitive and neuropsychiatric features of idiopathic normal pressure hydrocephalus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F23%3A10505355" target="_blank" >RIV/00216208:11130/23:10505355 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-031-36522-5_10" target="_blank" >https://doi.org/10.1007/978-3-031-36522-5_10</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-36522-5_10" target="_blank" >10.1007/978-3-031-36522-5_10</a>
Alternative languages
Result language
angličtina
Original language name
Cognitive and neuropsychiatric features of idiopathic normal pressure hydrocephalus
Original language description
Progressive cognitive impairment is one of the major symptoms of idiopathic normal pressure hydrocephalus (iNPH), present in about 80% of patients. Together with gait disturbance and urinary incontinence, cognitive impairment constitutes a part of the clinical triad. Cognitive deficit is commonly accompanied by neuropsychiatric symptoms (NPS), observed in up to 85% of the patients. Both cognitive deficits and neuropsychiatric symptoms are thought to result from frontal- subcortical dysfunction. The neuropsychological profile of iNPH is characterised by psychomotor slowing, reduced information processing speed, attention, working memory and executive deficit. The predominant NPS is apathy. Depending on the duration of symptoms, the cognitive continuum ranges from subtle selective cognitive decline to generalised dementia. In this chapter, we summarise the typical cognitive and neuropsychiatric profile associated with iNPH and describe the current cognitive and neuropsychiatric assessment standards. Implementation ofa shunt is a treatment option to improve symptoms and slow progression. We describe the evolution of cognitive and neuropsychiatric symptoms after shunting and the power of neuropsychological tests to predict the response to shunting. Finally, we discuss the role of neuropsychological assessment in differential diagnostics of iNPH.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Normal Pressure Hydrocephalus: Pathophysiology Diagnosis Treatment and Outcome
ISBN
978-3-031-36521-8
Number of pages of the result
27
Pages from-to
169-195
Number of pages of the book
578
Publisher name
Springer
Place of publication
Cham
UT code for WoS chapter
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