Reliability of Automated Intracranial Volume Measurements by Synthetic Brain MRI in Children
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F24%3A10481405" target="_blank" >RIV/00216208:11130/24:10481405 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TDM_vciSPk" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=TDM_vciSPk</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/app14114751" target="_blank" >10.3390/app14114751</a>
Alternative languages
Result language
angličtina
Original language name
Reliability of Automated Intracranial Volume Measurements by Synthetic Brain MRI in Children
Original language description
(1) Background: Hydrocephalus poses challenges in pediatric neuroimaging, and conventional MRI methods have limitations regarding its accurate quantification. Synthetic MRI (SyMRI) offers a promising automated solution to assess intracranial compartment volumes. However, its clinical utility in pediatric patients remains underexplored. Our study aims to assess the accuracy and reliability of automated CSF volume measurements using SyMRI in children and adolescents, comparing them with manual measurements and human expert ratings. (2) Methods: A single-center retrospective study included 124 pediatric patients undergoing cranial MRI with SyMRI. CSF, brain parenchyma, and intracranial volumes were measured using both automated SyMRI and manual methods. Human radiologists assessed hydrocephalus subjectively. (3) Results: Correlations between manual and SyMRI volume evaluations were significant. Human raters demonstrated good agreement on hydrocephalus ratings among themselves (Fleiss' kappa = 0.66, p < 0.001) but only moderate agreement with the SyMRI method (Cohen's kappa = 0.45, p < 0.001). SyMRI volumes were systematically tendentially higher in SyMRI (CSF p = 0.005; BPV and ICV p < 0.001). (4) Conclusions: Our findings highlight SyMRI's reliability in assessing hydrocephalus and intracranial volumes in pediatric cases. Despite some differences from manual measurements, the strong correlation suggests its clinical viability.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Sciences
ISSN
2076-3417
e-ISSN
2076-3417
Volume of the periodical
14
Issue of the periodical within the volume
11
Country of publishing house
CH - SWITZERLAND
Number of pages
15
Pages from-to
4751
UT code for WoS article
001246937400001
EID of the result in the Scopus database
2-s2.0-85195937634