All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

The dynamics of cancer stem cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F12%3A10123820" target="_blank" >RIV/00216208:11140/12:10123820 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.elis.sk/download_file.php?product_id=2991&session_id=jpa5s76uapba31c9g19nl9hbm7" target="_blank" >http://www.elis.sk/download_file.php?product_id=2991&session_id=jpa5s76uapba31c9g19nl9hbm7</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4149/neo_2012_092" target="_blank" >10.4149/neo_2012_092</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The dynamics of cancer stem cells

  • Original language description

    With the formulation of the hierarchical model of tumor cell organization, cancer stem cells came to the forefornt of cancer biology. As the only self-renewing tumor cells, they were made responsible for continuous tumor growth and their intrinsic self-protection ability was postulated to underlie cancer therapy resistance and/or recurrence. The concept of migrating cancer stem cells extended the relevance of the hierarchical cancer cell model to issue of cancer progression, with the crucial experimental evidence being provided by the demonstration that epithelial mesenchymal transition can convey stemness. Accordingly, cancer stem cells probably represent a highly dynamic cell population continuously differentiating and being continuously replenishedby processes like mesenchymal epithelial transition and epithelial mesenchymal transition, respectively. Consequently, from the point of view of therapeutic targeting, cancer stem cells obviously do not represent a fixed target population

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neoplasma

  • ISSN

    0028-2685

  • e-ISSN

  • Volume of the periodical

    59

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    7

  • Pages from-to

    700-707

  • UT code for WoS article

    000310820200014

  • EID of the result in the Scopus database