The dynamics of cancer stem cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F12%3A10123820" target="_blank" >RIV/00216208:11140/12:10123820 - isvavai.cz</a>
Result on the web
<a href="http://www.elis.sk/download_file.php?product_id=2991&session_id=jpa5s76uapba31c9g19nl9hbm7" target="_blank" >http://www.elis.sk/download_file.php?product_id=2991&session_id=jpa5s76uapba31c9g19nl9hbm7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2012_092" target="_blank" >10.4149/neo_2012_092</a>
Alternative languages
Result language
angličtina
Original language name
The dynamics of cancer stem cells
Original language description
With the formulation of the hierarchical model of tumor cell organization, cancer stem cells came to the forefornt of cancer biology. As the only self-renewing tumor cells, they were made responsible for continuous tumor growth and their intrinsic self-protection ability was postulated to underlie cancer therapy resistance and/or recurrence. The concept of migrating cancer stem cells extended the relevance of the hierarchical cancer cell model to issue of cancer progression, with the crucial experimental evidence being provided by the demonstration that epithelial mesenchymal transition can convey stemness. Accordingly, cancer stem cells probably represent a highly dynamic cell population continuously differentiating and being continuously replenishedby processes like mesenchymal epithelial transition and epithelial mesenchymal transition, respectively. Consequently, from the point of view of therapeutic targeting, cancer stem cells obviously do not represent a fixed target population
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
—
Volume of the periodical
59
Issue of the periodical within the volume
6
Country of publishing house
SK - SLOVAKIA
Number of pages
7
Pages from-to
700-707
UT code for WoS article
000310820200014
EID of the result in the Scopus database
—