Molecular advances in salivary gland pathology and their practical application

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F12%3A10128113" target="_blank" >RIV/00216208:11140/12:10128113 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.mpdhp.2012.08.002" target="_blank" >http://dx.doi.org/10.1016/j.mpdhp.2012.08.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mpdhp.2012.08.002" target="_blank" >10.1016/j.mpdhp.2012.08.002</a>

Result language

angličtina

Original language name

Molecular advances in salivary gland pathology and their practical application

Original language description

The review summarizes the new findings in salivary gland pathology with particular reference to molecular genetic developments. In particular, newly recognized entities and specific chromosomal translocations associated with salivary gland carcinomas arediscussed. Firstly, there are three types of salivary gland carcinomas which harbour important oncogenic translocations: mucoepidermoid carcinoma with the translocation t(11; 19)(q21; p13) CRTC1-MAML2 (as well as several other less frequent ones), adenoid cystic carcinoma with the translocation t(6; 9)(q22-23; p23-24) MYB-NFIB, and the recently described entity of mammary analogue secretory carcinoma (MASC) characterized by the translocation t(12; 15)(p13; q25) ETV6-NTRK3. Secondly, sclerosing polycystic adenosis was described in 1996 as possibly a salivary counterpart to benign fibrocystic disease of the breast, but recent molecular evidence of clonality suggests it is neoplastic in nature. Finally, new molecular developments in saliv

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Diagnostic Histopathology

ISSN

1756-2317

e-ISSN

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Volume of the periodical

18

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

388-396

UT code for WoS article

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EID of the result in the Scopus database

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