From mice to men: lessons from mutant ataxic mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10227214" target="_blank" >RIV/00216208:11140/14:10227214 - isvavai.cz</a>
Result on the web
<a href="http://www.cerebellumandataxias.com/content/1/1/4" target="_blank" >http://www.cerebellumandataxias.com/content/1/1/4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/2053-8871-1-4" target="_blank" >10.1186/2053-8871-1-4</a>

Result language
angličtina
Original language name
From mice to men: lessons from mutant ataxic mice
Original language description
Ataxic mutant mice can be used to represent models of cerebellar degenerative disorders. They serve for investigation of cerebellar function, pathogenesis of degenerative processes as well as of therapeutic approaches. Lurcher, Hot-foot, Purkinje cell degeneration, Nervous, Staggerer, Weaver, Reeler, and Scrambler mouse models and mouse models of SCA1, SCA2, SCA3, SCA6, SCA7, SCA23, DRPLA, Niemann-Pick disease and Friedreich ataxia are reviewed with special regard to cerebellar pathology, pathogenesis,functional changes and possible therapeutic influences, if any. Finally, benefits and limitations of mouse models are discussed.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)