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From mice to men: lessons from mutant ataxic mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10227214" target="_blank" >RIV/00216208:11140/14:10227214 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.cerebellumandataxias.com/content/1/1/4" target="_blank" >http://www.cerebellumandataxias.com/content/1/1/4</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/2053-8871-1-4" target="_blank" >10.1186/2053-8871-1-4</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    From mice to men: lessons from mutant ataxic mice

  • Original language description

    Ataxic mutant mice can be used to represent models of cerebellar degenerative disorders. They serve for investigation of cerebellar function, pathogenesis of degenerative processes as well as of therapeutic approaches. Lurcher, Hot-foot, Purkinje cell degeneration, Nervous, Staggerer, Weaver, Reeler, and Scrambler mouse models and mouse models of SCA1, SCA2, SCA3, SCA6, SCA7, SCA23, DRPLA, Niemann-Pick disease and Friedreich ataxia are reviewed with special regard to cerebellar pathology, pathogenesis,functional changes and possible therapeutic influences, if any. Finally, benefits and limitations of mouse models are discussed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cerebellum &amp; Ataxias

  • ISSN

    2053-8871

  • e-ISSN

  • Volume of the periodical

    Neuveden

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    21

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database