Foamy cell (hibernoma-like) change is a rare histopathological feature in renal cell carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F14%3A10282578" target="_blank" >RIV/00216208:11140/14:10282578 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/14:10282578
Result on the web
<a href="http://dx.doi.org/10.1007/s00428-014-1600-z" target="_blank" >http://dx.doi.org/10.1007/s00428-014-1600-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00428-014-1600-z" target="_blank" >10.1007/s00428-014-1600-z</a>
Alternative languages
Result language
angličtina
Original language name
Foamy cell (hibernoma-like) change is a rare histopathological feature in renal cell carcinoma
Original language description
We report nine patients (seven males and two females, median age 64 years (range 51-79 years)) with a renal cell carcinoma, each of which contained a significant component of neoplastic epithelial cells with a striking microvacuolated (hibernoma-like) cytoplasmic appearance. Tumor sizes ranged from 1.5 to 8.0 cm (mean 4.2 cm, median 4.3 cm). The basic architecture of the tumors was solid-alveolar in two cases (classified as renal cell carcinoma-not otherwise specified (NOS)) and papillary in seven cases(classified as papillary renal cell carcinoma NOS). The nuclear grade according to the Fuhrman grading system was three in all cases. By immunohistochemistry, the cells with microvacuolated cytopasm and significantly expressed adipophilin and anti-mitochondrial antigen in a similar cytoplasmic pattern. On ultrastructural examination, the cytoplasm of the neoplastic epithelial cells was packed with distended mitochondria, most of which displayed lamellated cristae. Numerous microvesicles
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedical Centre of the Faculty of Medicine in Pilsen</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Virchows Archiv : an international journal of pathology
ISSN
0945-6317
e-ISSN
—
Volume of the periodical
465
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
215-224
UT code for WoS article
000339950400011
EID of the result in the Scopus database
—