Microcirculation of the brain: morphological assessment in degenerative diseases and restoration processes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10282618" target="_blank" >RIV/00216208:11140/15:10282618 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1515/revneuro-2014-0049" target="_blank" >http://dx.doi.org/10.1515/revneuro-2014-0049</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/revneuro-2014-0049" target="_blank" >10.1515/revneuro-2014-0049</a>

Result language

angličtina

Original language name

Microcirculation of the brain: morphological assessment in degenerative diseases and restoration processes

Original language description

Brain microcirculation plays an important role in the pathogenesis of various brain diseases. Several specific features of the circulation in the brain and its functions deserve special attention. The brain is extremely sensitive to hypoxia, and brain edema is more dangerous than edema in other tissues. Brain vessels are part of the blood-brain barrier, which prevents the penetration of some of the substances in the blood into the brain tissue. Herein, we review the processes of angiogenesis and the changes that occur in the brain microcirculation in the most prevalent neurodegenerative diseases. There are no uniform vascular changes in the neurodegenerative diseases. In some cases, the vascular changes are secondary consequences of the pathological process, but they could also be involved in the pathogenesis of the primary disease and contribute to the degeneration of neurons, based on their quantitative characteristics. Additionally, we described the stereological methods that are mo

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EA - Morphology and cytology

OECD FORD branch

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Project

<a href="/en/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedical Centre of the Faculty of Medicine in Pilsen</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Reviews in the Neurosciences

ISSN

0334-1763

e-ISSN

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Volume of the periodical

26

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

19

Pages from-to

75-93

UT code for WoS article

000350396700006

EID of the result in the Scopus database

2-s2.0-84929085387