Persistent organochlorine pollutants in obese women after diet induced weight loss: five years follow up study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10312360" target="_blank" >RIV/00216208:11140/15:10312360 - isvavai.cz</a>

Alternative codes found

RIV/00669806:_____/15:10312360

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Persistent organochlorine pollutants in obese women after diet induced weight loss: five years follow up study

Original language description

Aim: Persistent organochlorine pollutants (POPs) from the environment are still bioaccumulating in human tissues. The aim of our study was to analyze the development of plasma POPs levels in obese women in relationship with their weight loss success in five year follow-up study. Methods: 20 obese women aged 25-73 years were studied just before and after having completed a 3 month controlled low calorie diet (LCD) intervention (5 MJ daily), and again after 6 and 60 months since the beginning of the study. Body weight and plasma levels of 7 POPs were measured: polychlorinated biphenyls (PCB) 153, 138, 180; 2,2-bis(4-chlorophenyl)-1,1,1-trichloroethylene (p,p-DDE); 2,2-bis(4-chlorophenyI)1,1,1-trichloroethane (p,p'-DDT), hexachlorocyclobenzene (HCB), hexachlorocyclohexane beta (HCH beta). Results: Data shows that after 3 months of a completely controlled restrictive diet regimen, the weight loss was associated with an increase in POP plasma levels. However, after a five year follow-up, there were no differences in POPs plasma levels between those who kept losing weight or maintained the initial weight (WL/M) and the group of weight gainers (WG), except for HCB where the WG had a significantly higher level (p < 0.05). Conclusions: These results suggest that contrary to the long-term weight gain, the long-term weight loss or weight maintenance caused by diet restriction is associated with lower plasma levels of HCB.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NT14330" target="_blank" >NT14330: Polychlorinated persistent organic pollutants in the etiopathogenesis of obesity and insulin resistance</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Central European Journal of Public Health

ISSN

1210-7778

e-ISSN

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Volume of the periodical

23

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

214-217

UT code for WoS article

000363071900007

EID of the result in the Scopus database

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