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Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F16%3A10324815" target="_blank" >RIV/00216208:11140/16:10324815 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006" target="_blank" >http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.anndiagpath.2016.04.006" target="_blank" >10.1016/j.anndiagpath.2016.04.006</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions

  • Original language description

    Twenty-one hidradenomas from 20 patients (13 female, 7 male) ranging in age from 18 to 87 years (mean, 57.75 years; median, 60 years) were studied for CRTC1-MAML2 and CRTC3-MAML2 fusions to find out whether there is a correlation between the particular cell type (polyhedral eosinophilic, clear, mucinous, epidermoid, and oncocytic) and presence the above alterations. CRTC1-MAML2 fusions were detected in 10 of the 21 neoplasms (47.6%). Fluorescence in situ hybridization for MAML2 break apart was analyzable in 13 specimens nd in all these specimens was positive, including 4 tumors with no demonstrable CRTC1-MAML2 fusion. n none of the cases was a CRTC3-MAML2 fusion detected. No obvious correlation between the cellular omposition and presence of t(11,19) translocation was found.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Annals of Diagnostic Pathology

  • ISSN

    1092-9134

  • e-ISSN

  • Volume of the periodical

    23

  • Issue of the periodical within the volume

    August

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    8-13

  • UT code for WoS article

    000380180400002

  • EID of the result in the Scopus database

    2-s2.0-84964755821