PET/MRI: Multiparametric imaging of brain tumors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F17%3A10363641" target="_blank" >RIV/00216208:11140/17:10363641 - isvavai.cz</a>
Alternative codes found
RIV/00669806:_____/17:10363641
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0720048X17300864?via%3Dihub" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0720048X17300864?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ejrad.2017.02.034" target="_blank" >10.1016/j.ejrad.2017.02.034</a>

Result language
angličtina
Original language name
PET/MRI: Multiparametric imaging of brain tumors
Original language description
A combination of morphological imaging of the brain with microstructural and functional imaging pro- vides a comprehensive overview of the properties of individual tissues. While diffusion weighted imaging provides information about tissue cellularity, spectroscopic imaging allows us to evaluate the integrity of neurons and possible anaerobic glycolysis during tumor hypoxia, in addition to the presence of accel- erated synthesis or degradation of cellular membranes; on the other hand, PET metabolic imaging is used to evaluate major metabolic pathways, determining the overall extent of the tumor ( 18 F-FET, 18 F-FDOPA, 18 F-FCH) or the degree of differentiation ( 18 F-FDG, 18 F-FLT, 18 F-FDOPA and 18 F-FET). Multi-parameter analysis of tissue characteristics and determination of the phenotype of the tumor tissue is a natural advantage of PET/MRI scanning. The disadvantages are higher cost and limited availability in all centers with neuro-oncology surgery. PET/MRI scanning of brain tumors is one of the most promising indications since the earliest experiments with integrated PET/MRI imaging systems, and along with hybrid imaging of neurodegenerative diseases, represent a new direction in the development of neuroradiology on the path towards comprehensive imaging at the molecular level.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)