Polymorphous adenocarcinoma of the salivary glands: reappraisal and update
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F18%3A10376067" target="_blank" >RIV/00216208:11140/18:10376067 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs00405-018-4985-5" target="_blank" >https://link.springer.com/article/10.1007%2Fs00405-018-4985-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00405-018-4985-5" target="_blank" >10.1007/s00405-018-4985-5</a>
Alternative languages
Result language
angličtina
Original language name
Polymorphous adenocarcinoma of the salivary glands: reappraisal and update
Original language description
Although relatively rare, polymorphous adenocarcinoma (PAC) is likely the second most common malignancy of the minor salivary glands (MiSG). The diagnosis is mainly based on an incisional biopsy. The optimal treatment comprises wide surgical excision, often with adjuvant radiotherapy. In general, PAC has a good prognosis. Previously, PAC was referred to as polymorphous low-grade adenocarcinoma (PLGA), but the new WHO classification of salivary gland tumours has also included under the PAC subheading, the so-called cribriform adenocarcinoma of minor salivary glands (CAMSG). This approach raised controversy, predominantly because of possible differences in clinical behaviour. For example, PLGA (PAC, classical variant) only rarely metastasizes, whereas CAMSG often shows metastases to the neck lymph nodes. Given the controversy, this review reappraises the definition, epidemiology, clinical presentation, diagnostic work-up, genetics, treatment modalities, and prognosis of PAC of the salivary glands with a particular focus on contrasting differences with CAMSG.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Archives of Oto-Rhino-Laryngology
ISSN
0937-4477
e-ISSN
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Volume of the periodical
275
Issue of the periodical within the volume
7
Country of publishing house
DE - GERMANY
Number of pages
15
Pages from-to
1681-1695
UT code for WoS article
000434707600003
EID of the result in the Scopus database
2-s2.0-85046889465