Experimental neurotransplantation for cerebellar ataxias

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F23%3A10471110" target="_blank" >RIV/00216208:11140/23:10471110 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/978-3-031-24345-5_18" target="_blank" >https://doi.org/10.1007/978-3-031-24345-5_18</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-24345-5_18" target="_blank" >10.1007/978-3-031-24345-5_18</a>

Result language
angličtina
Original language name
Experimental neurotransplantation for cerebellar ataxias
Original language description
Neurotransplantation is one of the therapeutic methods for cerebellar diseases that are currently being intensively investigated. Despite years of research, there are still many questions to be answered. Compared to transplantation of other tissues and organs, neurotransplantation has some specific challenges, and these are particularly demanding for the cerebellum. In this chapter, the goals of neurotransplantation, its mechanisms underlying graft effects, the types of grafts, as well as the problems of graft survival, differentiation and functional integration are discussed. Different requirements and limitations of neurotransplantation therapy related to different types of pathologies are also discussed. Finally, overview of neurotransplantation research employing animal models of diseases during past decades is provided.
Czech name
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Czech description
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Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Trials for Cerebellar Ataxias. From Cellular Models to Human Therapies
ISBN
978-3-031-24344-8
Number of pages of the result
30
Pages from-to
469-498
Number of pages of the book
727
Publisher name
Springer Nature
Place of publication
Cham
UT code for WoS chapter
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