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Simultaneous infusion of glutamine and branched-chain amino acids (BCAA) to septic rats does not have more favorable effect on protein synthesis in muscle, liver and small intestine than separate infusions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F06%3A00004024" target="_blank" >RIV/00216208:11150/06:00004024 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/06:00006922

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Simultaneous infusion of glutamine and branched-chain amino acids (BCAA) to septic rats does not have more favorable effect on protein synthesis in muscle, liver and small intestine than separate infusions

  • Original language description

    In septic rats we observed a decrease in glutamine concentration in blood and muscle, a decrease in BCAA in liver and jejunum and a decrease in protein synthesis in all tissues. Glutamine or glutamine+BCAA infusion increased glutamine concentration in plasma and muscle and stimulated protein synthesis in the liver. The BCAA infusion enhanced concentrations of BCAA in blood and tissues, the effect on protein synthesis was insignificant. Synergistic effect of glutamine and BCAA on protein synthesis was not observed.

  • Czech name

    Simultánní infúze glutaminu a aminokyselin s rozvětveným řetězcem (BCAA) septickým potkanům nemá významně příznivější vliv na proteosyntézu ve svalu, játrech a tenkém střevu než jejich samostatné podání

  • Czech description

    U potkanů se sepsí byl pozorován pokles koncentrace glutaminu v krvi a svalu, pokles BCAA v játrech a jejunu a pokles proteosyntézy ve všech sledovaných tkáních. Infúze glutaminu či glutaminu+BCAA vedla ke vzestupu koncentrace glutaminu v krvi a svalu astimulaci proteosyntézy v játrech. Infúze BCAA navodila vzestup koncentrací BCAA v krvi a tkáních, vliv na proteosyntézu nebyl prokázán. Synergistický vliv souběžné infúze glutaminu a BCAA na proteosyntézu nebyl prokázán.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Parenteral and Enteral Nutrition

  • ISSN

    0148-6071

  • e-ISSN

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    467-473

  • UT code for WoS article

  • EID of the result in the Scopus database