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Anthracycline cardiotoxicity and the possibility of the pharmacological cardioprotection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F07%3A00003592" target="_blank" >RIV/00216208:11150/07:00003592 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Anthracycline cardiotoxicity and the possibility of the pharmacological cardioprotection

  • Original language description

    In this study, the potential cardioprotective properties of novel lipophilic aroylhydrazone chelators (pyridoxal 2-chlorobenzoyl hydrazone, salicylaldehyde isonicotinoyl hydrazone) as well as dexrazoxane (model cardioprotectant) and deferiprone (novel clinically used iron chelator) were studied on the rabbit model of chronic anthracycline cardiotoxicity.

  • Czech name

    Antracyklinová kardiotoxicita a možnosti farmakologické kardioprotekce

  • Czech description

    V této studii byly studovány potenciální kardioprotektivní vlastnosti nových lipofilních aroylhydrazonových chelátorů (pyridoxal 2-chlorbenzoyl hydrazonu, salicylaldehyd isonikotinoyl hydrazonu), stejně tak dexrazoxanu (modelového kardioprotektiva) a deferipronu (nového klinicky užívaného chelátoru železa) na modelu chronické antracyklinové kardiotoxicity u králíka.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FR - Pharmacology and apothecary chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers of the Faculty of Medicine of Palacky University

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    151

  • Issue of the periodical within the volume

    Suppl. 1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    2

  • Pages from-to

    69-70

  • UT code for WoS article

  • EID of the result in the Scopus database