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Changes of cholinesterase activities in the plasma and some tissues following administration of L-carnitine and galanthamine in rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F07%3A00003763" target="_blank" >RIV/00216208:11150/07:00003763 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/07:00000343

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Changes of cholinesterase activities in the plasma and some tissues following administration of L-carnitine and galanthamine in rats

  • Original language description

    Changes of cholinesterase (Ache) activities in the hypophysis and brain (frontal cortex, hippocampus, medial septum and basal ganglia) as well as in the plasma and liver following galanthamine administration were studied in rats pretreated with L-carnitine. Following galanthamine administration the Ache activities decreased in the tissues. Pretreatment with L-carnitine showed higher Ache inhibition, statistically significant difference was observed in hippocampus, only

  • Czech name

    Změny aktivity cholinesterasy v plasmě a některých tkáních po podání L-carnitinu a galantaminu krysám

  • Czech description

    Sledovali jsme změny aktivity cholinesteras v hypofyze a různých částech mozkové tkáně, v jaterní tkáni a v plasmě po podání galantaminu u krys a u krys s předchozím podání L-karnitinu. Podání galantaminu vede k poklesu aktivity Ache v tkáních, ne však vplasmě. Předchozí podání L-carnitinu zvýší inhibiční účinek galantaminu, signifikantní rozdíl jsme nalezli v hipokampu.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR7935" target="_blank" >NR7935: Interactions of galanthamine with modulators of membrane transport in the central nervous system</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroscience Letters

  • ISSN

    0304-3940

  • e-ISSN

  • Volume of the periodical

    411

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    5

  • Pages from-to

    212-216

  • UT code for WoS article

  • EID of the result in the Scopus database