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Effect of S-adenosylmethionine on acetaminophen-induced toxic injury of rat hepatocytes in vitro

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F09%3A00208542" target="_blank" >RIV/00216208:11150/09:00208542 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of S-adenosylmethionine on acetaminophen-induced toxic injury of rat hepatocytes in vitro

  • Original language description

    The study evaluates a possible protective effect of S-adenosylmethionine (SAMe) against acetaminophen-induced toxic injury of primary rat hepatocytes. Co-incubation of hepatocytes with SAMe improved their functional indicators - urea and albumin production. SAMe also abolished the decrease in the mitochondrial respiration (Complex II) induced by acetaminophen.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Veterinaria Brno

  • ISSN

    0001-7213

  • e-ISSN

  • Volume of the periodical

    78

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    11

  • Pages from-to

  • UT code for WoS article

    000273634200007

  • EID of the result in the Scopus database