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Mechanisms participating in oxidative damage of isolated rat hepatocytes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F09%3A00208707" target="_blank" >RIV/00216208:11150/09:00208707 - isvavai.cz</a>

  • Alternative codes found

    RIV/67985823:_____/09:00338637 RIV/00216275:25310/09:00009093

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mechanisms participating in oxidative damage of isolated rat hepatocytes

  • Original language description

    The aim of the study was to evaluate time course and dose dependence of peroxidative damage induced by tert-butyl hydroperoxide in rat hepatocytes. Our data showed that the most sensitive indicators of the peroxidative damage are changes of cytosolic glutathione concentration and mitochondrial membrane potential. Succinate-dependent oxidation was most resistant to peroxidative damages.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA303%2F06%2F1261" target="_blank" >GA303/06/1261: Pathophysiological function of mitochondrial glycerophopsphate dehydrogenase - production of reactive oxygen species</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Archives of Toxicology

  • ISSN

    0340-5761

  • e-ISSN

  • Volume of the periodical

    83

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000264883800009

  • EID of the result in the Scopus database